

A higher-potency formula for particular moments, deeper challenges, and more complex inner terrain
The most potent microdosing formula, reserved for experienced practitioners seeking a more intensive microdosing protocol. Developed for specific situations where a higher dose is appropriate, it is intended to be approached with experience, intention, and care.
Enriched with Lion's Mane fruit bodies to support focus, integration, and cognitive performance; and niacin to support distribution and cellular energy production.
High-potency psilocybin mushroom blend (whole fruiting body), 330 mg per capsule;
Lion's Mane (Hericium erinaceus, whole fruiting body) — a nootropic mushroom studied for nerve-growth factor and cognitive support; it complements psilocybin's effect on neuroplasticity;
Niacin (Vitamin B3) — supports distribution of active compounds and cellular energy production.
All ingredients are 100% natural, organic, sustainably grown, and vegan. No fillers, no synthetic additives. Every batch is tested for potency and purity.
The experience becomes more apparent; the subtle shifts often associated with microdosing may become easier to recognize, with greater mental clarity, emotional openness, creative flow, and a heightened sense of presence throughout the day.
The dose remains sub-perceptual, yet asks for greater awareness and responsibility.
Microdosing follows a rhythm of dosing and rest. Intervals between doses help maintain sensitivity and create space to observe the effects over time. Two established approaches:
The 1-2 protocol — one day on, then two days off. The on day is the microdose day; the day after often carries a subtle "afterglow"; the second is a full reset. Gentle, easy to track, and the most common way to begin.
The 4-2 protocol — four days on, two days off. A steadier, deeper, more consistent rhythm favored for sustained focus and mood support.
On dosing days, take one capsule in the morning on an empty stomach.
Avoid microdosing if you:
If you take any prescription medication, consult a qualified healthcare professional before starting.
Taking antidepressants or psychiatric medication (SSRIs, SNRIs, MAOIs, tricyclics) may blunt the effects or cause interactions. Lithium and tramadol are dangerous combinations and must be avoided.
Approach the experience with patience, consistency, and enough space for it to unfold naturally


Create room around deeply established patterns and explore perspectives that may be inaccessible from within them


Approach difficult thoughts, emotions, and inner material with greater openness and curiosity


Step outside familiar interpretations and explore new ways of understanding yourself, your circumstances, and what comes next
Microdosing means taking a very small, precisely measured amount of a natural medicine, usually about a tenth of a regular dose, on a steady schedule with rest days built in. In Nagua products, the active ingredient is psilocybin, naturally occurring in the fruiting bodies of the mushroom. The amount is intended to remain below the threshold of a full psychedelic experience, allowing you to go about your normal life while exploring subtler changes in mood, clarity, attention, and openness.
Psilocybin can interact with certain medications and may not be appropriate for everyone. If you take antidepressants, especially SSRIs or lithium, have a serious heart condition, are pregnant or breastfeeding, are under 21, or have a personal or family history of psychosis or bipolar disorder, speak with a qualified healthcare professional before considering microdosing. If you take any regular medication or have a medical condition not mentioned here, we recommend checking with your doctor first.
There is no single moment when it suddenly "starts working." Microdosing is subtle by nature, and changes often reveal themselves gradually, through small shifts in the way you think, feel, respond, or move through everyday life. Some people notice something within the first few weeks; for others, the changes become clearer only with time and consistency.
If microdosing is new to you, we recommend beginning with Teo (I.), created as a gentle introduction to the medicine and a way to become familiar with its subtler effects. If you already have experience with microdosing, Teo (II.) offers a deeper step into the territory. If you are unsure where to begin or would like to talk through your starting point, contact us and we'll be happy to help you find the right place to start.
Microdosers scored lower on dysfunctional attitudes and negative emotionality, and higher on wisdom, open-mindedness and creativity, than non-microdosing controls.
Across 8,703 adults, microdosers with mental-health concerns reported lower depression, anxiety and stress than non-microdosing peers, with health the leading motive.
In an eight-week randomized, placebo-controlled trial, weekly low-dose psilocybin significantly reduced dysfunctional attitudes — the rigid beliefs behind stuck patterns.
In 233 adults tracked across a month of microdosing, trait mindfulness rose steadily week by week, reaching the level typically seen across the general population.
Over four weeks of microdosing, 81 participants reported steadily rising wellbeing and psychological flexibility, alongside falling depression and state anxiety.
Across hundreds of self-reported accounts, microdosers most often described deeper empathy, closer relationships, and a stronger connection to nature and others.